姓 名:卿志和
职 称:教授
导师资格:博士生导师
邮 箱:qingzhihe@hnu.edu.cn
电 话:0731-85258649
研究方向:生物传感与健康分析
简介:卿志和,教授,博士生导师,国家优秀青年科学基金获得者,“细胞化学”湖南省重点实验室常务副主任,“健康化学”湖南省普通高等学校科技创新团队带头人,bat365在线唯一官网登录“湖湘学者”拔尖人才、科技处副处长、化学化工学院教授委员会主任、化学生物学专业负责人,入选全球前2%顶尖科学家榜单。从事生物传感与健康分析研究工作,已主持国家自然科学基金优青项目、面上项目,湖南省自然科学基金重点项目、优青项目、企业技术服务项目等课题10余项,在 PNAS、Angew Chem、Anal Chem、等国内外高水平期刊上发表SCI收录论文80余篇,授权专利10余件。获得湖南省自然科学一等奖、湖南省自然科学二等奖、湖南省青年科技奖、湖南省教育系统优秀共产党员、湖南省优秀研究生导师等奖励或荣誉。担任Chinese Chemical Letters、The Innovation、Journal of Analysis and Testing、《分析试验室》等国内外期刊的编委或青年编委。
代表性论文:
[1] Quan Ke; Li Xiaoyuan; Deng Jiaqi; Chen Weiju; Zou Zhen; Chen Kun; Wu Linlin; Liu Juewen;Qing Zhihe*. Pt-Decorated Gold Nanoflares for High-Fidelity Phototheranostics: Reducing Side-Effects and Enhancing Cytotoxicity toward Target Cells, Angew. Chem. Int. Ed. 2024, 63, e202402881.
[2] Yanli Lei, Chuangchuang Li, Xinyue Ji, Haiyan Sun, Xiaowen Liu, Zenghui Mao, Weiju Chen, Zhihe Qing,* and Juewen Liu. Lowering Entropic Barriers in Triplex DNA Switches Facilitating Biomedical Applications at Physiological pH. Angew. Chem. Int. Ed. 2024, 63 , e202402123.
[3] Yibo Zhou, Zhengxuan Gu, Changhui Liu, Sheng Yang,* Xiaofei Ma, Qiaoshu Chen, Yanli Lei, Ke Quan, Juewen Liu, Zhihe Qing,* Ronghua Yang*. A Polymeric Nanobeacon for Revealing Hydrogen Polysulfides Fluctuation during Fertilization and Embryonic Development. Angew. Chem. Int. Ed. 2022, 61, e202114504.
[4] Zhen Zou, Libei He, Xiangxi Deng, Huangxiang Wang, Ziyun Huang, Qian Xue, Zhihe Qing*, Yanli Lei, Ronghua Yang*, and Juewen Liu. Zn2+-Coordination-Driven RNAAssembly with Retained Integrity and Biological Functions. Angew. Chem. Int. Ed. 2021, 60, 22970–22976.
[5] Lifang Chen, Shuohui Xing, Yanli Lei, Qiaoshu Chen, Zhen Zou, Ke Quan, Zhihe Qing*, Juewen Liu, and Ronghua Yang*. A Glucose-Powered Activatable Nanozyme Breaking pH and H2O2 Limitations for Treating Diabetic Infections. Angew. Chem. Int. Ed. 2021, 60, 23534–23539.
[6] Zhihe Qing, Guoyan Luo, Shuohui Xing, Zhen Zou, Yanli Lei, Juewen Liu*, Ronghua Yang*. Pt-S Bond Mediated Nanoflares for High-Fidelity Intracellular Applications by Avoiding Thiol Cleavage. Angew. Chem. Int. Ed.2020, 59, 14044 –14048.
[7] Zhihe Qing*, Jinlei Hu, Jingyuan Xu, Zhen Zou, Yanli Lei, Taiping Qing, Ronghua Yang*. An intramolecular catalytic hairpin assembly on a DNA tetrahedron for mRNA imaging in living cells: improving reaction kinetics and signal stability. Chem. Sci. 2020, 11, 1985–1990.
[8] Zhihe Qing*, Jingyuan Xu, Jing Zheng, Lei He, Zhen Zou, Sheng Yang, Weihong Tan, Ronghua Yang*. In Situ Amplification-Based Imaging of RNA in Living Cells. Angew. Chem. Int. Ed. 2019, 58, 11574–11585.