姓 名:全珂
职 称:讲师
导师资格:硕士生导师
邮 箱:quanke518@126.com
电 话:15675185142
研究方向:(1) 基于CRISPR-Cas系统的便携式检测新方法的构建;(2)功能核酸/纳米酶在食品安全分析中的应用;(3)治病菌的可视化检测与防控
简介:全珂,理学博士,讲师,硕士生导师。bat365在线唯一官网登录“湖湘学者”青年英才,获评bat365在线唯一官网登录优秀党支部书记、“双带头人”标兵。主持国家自然科学基金青年项目、湖南省自然科学基金青年项目、长沙市自然科学基金(优先资助)、湖南省教育厅优青项目等课题共6项。在JACS、Angew. Chem. Int. Ed.、 Chem. Sci.、CCS Chem.等SCI期刊发表论文40余篇。指导学生获得全国大学生生命科学竞赛全国三等奖2项,省级三等奖2项。
代表性论文:
(1) Quan Ke; Li Xiaoyuan; Deng Jiaqi; Chen Weiju; Zou Zhen; Chen Kun; Wu Linlin; Liu Juewen;Qing Zhihe*. Pt-Decorated Gold Nanoflares for High-Fidelity Phototheranostics: Reducing Side-Effects and Enhancing Cytotoxicity toward Target Cells, Angewandte Chemie International Edition, 2024, 63:e202402881.
(2) Gao Yuan; Bai Bingfeng; Mao Zenghui; Yang Xiao; Shi Yi; Zhang Bo; Quan Ke*; Qing Zhihe*. An all-in-one Smartphone-assisted Ratiometric Fluorescent Device for Visual and Quantitative Detection of Glutathione, Talanta, https://doi.org/10.1016/j.talanta.2024.126805
(3) Quan Ke; Zeng Yuqing; Zhang Wenke; Li Fengfeng; Li Mengjiao; Qing Zhihe*. One-step, reagent-free construction of nano-enzyme as visual and reusable biosensor for oxidase substrates, Analytica Chimica Acta, 2024, 1285: 342008.
(4) Quan Ke; Tong Jiajie; Chen Lifang; Fang Shuyao; Li Mengjiao; Wu Linlin; Qing Zhihe*. Freezing-directed construction of enzyme/nano interfaces: Reagentless conjugation, superior activity, and better stability, Chinese Chemical Letters, 2024, 35: 108894.
(5) Quan Ke; Wang Jiaoli; Li Jing; Wang Kemin; Huang Jin*. An endogenous miRNA-initiated hybridization chain reaction and subsequent DNAzyme activation for cellular theranostics,CCS Chemistry, 2022, 4:3505-3515.
(6) Quan Ke; Yi Cuiping; Yang Xiaohai; He Xiaoxiao; Huang Jin*; Wang Kemin*. FRET- based nucleic acid probes: Basic designs and applications in bioimaging, TrAC Trends in Analytical Chemistry, 2020, 124: 115784.
(7) Quan Ke; Li Jing; Wang Jiaoli; Xie Nuli; Wei Qiaomei; Tang Jinlu; Yang Xiaohai; Wang Kemin; Huang Jin*; Dual-microRNA-controlled double-amplified cascaded logic DNA circuits for accurate discrimination of cell subtypes. Chemical Science, 2019, 10: 1442-1449.
(8) Quan Ke; Huang Jin*; Yang Xiaohai; Yang Yanjing; Ying Le; Wang He; Xie Nuli; Ou Min; Wang Kemin*; Powerful amplification cascades of FRET-based two-layer nonenzymatic nucleic acid circuits. Analytical Chemistry, 2016, 88: 5857-5864.
(9) Quan Ke; Huang Jin; Yang Xiaohai; Yang Yanjing; Ying Le; Wang He; He Yong; Wang Kemin*; An enzyme-free and amplified colorimetric detection strategy via target-aptamer binding triggered catalyzed hairpin assembly. Chemical Communications, 2015, 51: 937-940.